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(APOLOGIES in advance for the less-than-ideal audio on this video clip. This is not normal.)
Preclinical studies have shown that, during menopausal transition, the estrogen network uncouples from the brain bioenergetic system. The resulting hypometabolic state could serve as the substrate for neurological dysfunction. Indeed, translational brain imaging studies demonstrate that 40-60 year-old perimenopausal and postmenopausal women exhibit an Alzheimer’s disease phenotype characterized by decreased metabolic activity and increased brain beta amyloid deposition as compared to premenopausal women and to age-matched men. This presentation will discuss the menopausal transition as a window of opportunity for therapeutic interventions to compensate for the brain bioenergetic crisis and combat the subsequent increased risk for Alzheimer’s disease in women.
About Dr. Filomena Trindade, MD, MPH
Dr. Filomena Trindade, MD, MPH, ABAARM, ABFM, FMNM is a teacher, author, and international speaker in functional medicine. She is a graduate of the fellowship in Anti-Aging, Regenerative and Functional Medicine and teaches in the Fellowship (a Master’s program through the Morsani School of Medicine, University of South Florida).
In addition, she is faculty at the Institute for Functional Medicine (IFM). After obtaining her BA degree in Biology she went on to finish a Master’s in Public Health in the area of environmental health and epidemiology before starting medical school. She graduated first in her class in family practice from the University of California Davis School of Medicine and did her residency training in family practice at the U.C. San Francisco/Santa Rosa Program. She has been in clinical practice for over 20 years. Before starting her own private practice in 2004 in functional medicine she was the medical director of a non-profit organization that catered to the underserved. Her work has been published in Townsend Letter, Guide to Anti-Aging & Regenerative Medicine, Saúde Actual, and the Border Health Journal among others. She is currently very active in developing teaching programs in Functional Medicine in the USA, Latin America and Europe. Keep up with her activities at www.drtrindade.com.
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